Research Articles
VideoFreeze and DeepLabCut Integration: A Complete Validation Guide for Quantifying Animal Behavior in Preclinical Research
This article provides a comprehensive validation and application guide for integrating the VideoFreeze fear-conditioning system with DeepLabCut (DLC) for advanced, markerless motion capture in preclinical behavioral neuroscience and drug discovery.
A Complete Guide to TRACULA: Automating White Matter Reconstruction with FreeSurfer for Neuroscientists
This comprehensive guide details the TRACULA (TRActs Constrained by UnderLying Anatomy) tool within FreeSurfer, a fully automated probabilistic pipeline for reconstructing major white matter pathways.
A Comprehensive Guide to TBSS (FSL): From Protocol to Clinical Application in Neuroimaging Research
This article provides a complete roadmap for implementing Tract-Based Spatial Statistics (TBSS) using the FSL software suite, targeted at researchers and drug development professionals.
Sternberg Task EEG: A Neural Biomarker for Quantifying Cognitive Reserve in Neurodegenerative Disease Research
This article synthesizes current research on the combined use of the Sternberg memory task and electroencephalography (EEG) to operationalize and measure cognitive reserve (CR).
SPHARA: A Guide to Spatial Harmonic Analysis for Denoising Dry EEG in Clinical Research
This article provides a comprehensive guide to Spatial Harmonic Analysis (SPHARA) for enhancing the signal quality of dry electroencephalography (EEG) data.
Mapping the Mind: The Neural Correlates of Raven's Progressive Matrices in Human Intelligence Research
This article provides a comprehensive review of the current neurobiological understanding of Raven's Progressive Matrices (RPM), a gold-standard measure of non-verbal abstract reasoning and fluid intelligence.
Advanced ROI-Based Variance Estimation in DTI: A Comprehensive Guide for Neuroimaging Researchers
This article provides a comprehensive guide to Region-of-Interest (ROI)-based methods for estimating variance in Diffusion Tensor Imaging (DTI), a critical yet often overlooked component of robust neuroimaging analysis.
Beyond the DSM: Implementing the RDoC Framework for Revolutionary Brain Network Research and Precision Psychiatry
This article provides a comprehensive guide for researchers and drug development professionals on implementing the NIMH's Research Domain Criteria (RDoC) framework within modern brain network research.
The Essential PreQual Pipeline: A Complete Guide to Automated DTI Preprocessing and Quality Assurance for Neuroimaging Research
This comprehensive guide explores the PreQual (Preprocessing and Quality Assurance) pipeline, an open-source, containerized tool for standardized and automated Diffusion Tensor Imaging (DTI) preprocessing.
Computer Vision in Biomedical Research: OpenCV vs. Photogrammetric Bundle Adjustment for 3D Reconstruction & Calibration
This article provides a comprehensive technical comparison between the widely-used OpenCV calibration modules and rigorous photogrammetric bundle adjustment methods, tailored for biomedical researchers and drug development professionals.